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Pharmacology Central Nervous system c06b38ad

All are true about ramelteon except:

A
Agonist at MT1 and MT2 receptors
B
Is a substrate of CYP1A2
C
Has high addiction liability
D
Approved for treatment of insomnia
High-Yield Explanation
Ref:katzung 11/e p374 Ramelteon is non-addictive drug. Ramelteon, marketed as Rozerem among others, is a sleep agent that selectively binds to the MT1 and MT2 receptors in the suprachiasmatic nucleus (SCN), instead of binding to GABAA receptors, such as with drugs like zolpidem. Ref: KD Tripathi 8th ed.

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