Which of the following statements is true regarding pertussis -
High-Yield Explanation
Pertussis (Whooping Cough):
Leukocytosis does not correlates with the severity of cough
Drug of choice: Erythromycin (40 mg/kg QID X 10 days)
Vaccines:
DPT:
i. Killed acellular bacilli 20,000 million per dose (0.5 ml)
ii. Pertussis component leads to neurological complications after 2 years of age (@ 1 per 1,70,000 vaccinees)
iii. Vaccine efficacy is 50 – 60 % (2 doses) and 70% (3 doses)
Pertussis killed whole cell vaccine
DOC for cases and contacts: Erythromycin (for 10 days)