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Biochemistry General c032e32a

Which one of the following TCA cycle intermediate may not be added or removed by other metabolic pathways?

A
Oxaloacetate
B
Isocitrate
C
Citrate
D
Fumarate
High-Yield Explanation
Oxaloacetate may be formed from pyruvate during gluconeogenesis. Degradation of tyrosine and phenylalanine may produce fumarate. Citrate is transpoed out of mitochondria to be used as a source of cytoplasmic acetyl CoA. Isocitrate is formed and removed in TCA cycle. Ref: Textbook of Biochemistry for Medical Students by D.M. Vasudevan, 6th Edition, Page: 218

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