A 60 year old woman presents with generalized edema, Skin Ulceration and hypeension. Urine examination shows subnephrotic proteinuria (<2gm) and microscopic haematuria. serum complement levels are decreased and she is positive for anti-hepatitis c antibodies. The likely diagnosis is -
High-Yield Explanation
Acute post streptococcal glomerulonephritis is an immunologic response of the kidney to infection, characterized by the sudden appearance of edema, hematuria, proteinuria and hypeension . It is essentially a disease of childhood that accounts for approximately 90% of renal disorders in children. Ref Harrison20th edition pg 278