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Pharmacology Cardiovascular system bfdae167

Drug ezetimibe act by?

A
Enhancing excretion of bile acids
B
Decreasing absorption of cholesterol
C
Inhibiting HMG-CoA
D
Inhibiting intracellular lipase
High-Yield Explanation
Ezetimibe acts by inhibiting the intestinal absorption of cholesterol and phytosterols. It interferes with a specific CH transpo protein NPC1C1 in the intestinal mucosa and reduces the absorption of both dietary and biliary CH. (REF. ESSENTIALS OF MEDICAL PHARMACOLOGY K.D TRIPATHI-6th edition.Page No-618)
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