Full 2L QBank
Pathology Miscellaneous (Blood Vessels) bf3f5204

Endothelium activation refers to -

A
Aberration of anatomy of vessel wall
B
Irreversible changes in functional state of vessel wall
C
Smooth muscle proliferation
D
Increased expression of adhesion molecules for leukocyte recruitment
High-Yield Explanation
Ans. is 'd' i.e., Increased expression of adhesion molecules for leukocyte recruitment o Vascular endothelium in its normal, unactivated state does not bind circulating cells or impede their passage,o In acute inflammation, the endothelium is activated and can bind leukocytes as a prelude to their exit from the bloodvessels.o Inflammatory mediators like thrombin, IL - 1, Platelet Activating Factor, Histamine And TNFactivate endothelial cells by increasing expression of adhesion molecules which can bind leukocytes for leukocyte recruitment.

Related Pathology MCQs

Practice 2,00,000+ NEET PG Questions Free

Timed mock tests, mistake queue analytics, audio lectures & zero attempt limits on i❤️Exams.

Start Free Mock Test Now