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Pharmacology Hematology bf191637

All of the following cause hypeension except

A
NSAID
B
L-Dopa
C
Cyclosporine
D
Erythropoietin
High-Yield Explanation
NSAIDS- Cause retention of sodium and water causing edema and also decreases the effects of antihypeensive drugs. Hypeension is more common in coxib users than NSAIDS. Cyclosporine- May cause hypeension in 50% of renal transplants and in almost all cardiac transplants. L-Dopa- Peripheral decarboxylation of L-Dopa releases dopamine which in circulation may activate vascular dopamine receptors and cause ohostatic hypotension. Administration of Ldopa with nonspecific MAO inhibitors may precipitate a hypeensive crisis and hyperpyrexia. Drugs Causing Hypeension a. Clonidine withdrawal b. Coicotropin c. Cyclosporine d. Erythropoietin e. MAO inhibitors with sympathomimetic f. NSAIDS (some) g. OCP h. Sympathomimetic i. TCA with sympathomimetics

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