A 7-year-old girl is brought with complaints of generalized swelling of the body. Urinary examination reveals grade 3 proteinuria and the presence of hyaline and fatty casts. She has no history of hematuria. Which of the following statements about her condition is true –
High-Yield Explanation
This girl is having
Generalized swelling (oedema)
Grade 3 proteinuria
Fatty casts (lipiduria)
No hematuria
All these features suggest the diagnosis of nephrotic syndrome.
Minimal change disease is the commonest cause of nephrotic syndrome in children.
Minimal change disease is characterized by the absence of IgG deposits and/or complement on immunofluorescence.