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General Medicine General bef08226

All of the following are true about HMG CoA reductase inhibitors except:

A

CNS accumulation of simvastatin and lovastatin is high and less for pravastatin and fluvastatin

B

Simvastatin is rapidly and pravastatin is least metabolized.

C

Bioavailability is minimally modified when pravastatin is taken with food

D

Fibrinogen levels are increased by pravastatin

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