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Physiology Endocrinology and Reproduction be363669

Excess secretion of aldosterone causes all except:

A
Increased ECF
B
Very High Na+ in plasma
C
Increased BP
D
Natriuresis
High-Yield Explanation
Ans. (b) Very High Na+ in plasma(Ref: Ganong, 25th ed/p.370)Excess aldosterone causes Sodium and water retentionIn spite of action of aldosterone on the renal tubules, Sodium excretion is increased during aldosterone excess - "Aldosterone Escape phenomenon"This is because of the increase in atrial natriuretic peptide (ANP) secretion that excretes sodium in response to increase in ECF volumeSo, Very High Na+ in plasma is not seen in aldosterone excess

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