Not seen in osteogenesis imperfecta
High-Yield Explanation
- Osteogenesis imperfecta is a type- 1 collagen defect which affects the tensile strength of the bone.it most commonly occurs in femur. It leads to weakening of bones. - Thin coex is the hallmark for osteogenesis imperfecta. - Deformities occurring in osteogenesis imperfecta includes saber shin (bowing), Coxa vara (decreased neck- shaft angle of femur) and Wormian bones (sho, dot- like). - Wormian bones are also found in down syndrome, osteogenesis imperfecta, trisomy and skeletal dysplasia