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Physiology Glomerular Filtration, Renal Blood Flow, and Their Control be02446a

Effect of dopamine on renal vessels -

A
Vasodilatation
B
Vasoconstriction
C
Increased permeability
D
No effect
High-Yield Explanation
Ans. is 'a' i.e., Vasodilatation o The physiologic function of the dopamine in the circulation is unknown.o However, injected dopamine produces renal vasodilation, probably by acting on a specific dopaminergic receptor,o It also produces vasodilation in the mesentery.o Elsewhere; it produces vasoconstriction, probably by releasing norepinephrine, and it has a positive inotropic effect on the heart by an aciton on b1-adrenergic receptors.o The net effect of moderate doses of dopamine is an increase in systolic pressure and no change in diastolic pressure.o Because of these actions, dopamine is useful in the treatment of traumatic and cardiogenic shock.

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