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Gynaecology & Obstetrics General bddca572

Which of the following statement regarding Prolactin levels is TRUE?

A
Lowest in pregnancy and increases after delivery
B
Highest during pregnancy and fall during lactation
C
Unaffected by pregnancy and lactation
D
Variable in every pregnancy
High-Yield Explanation
Maternal plasma levels of prolactin increase markedly during normal pregnancy and concentrations are usually 10-fold greater at term--about 150 ng/mL--compared with nonpregnant women. Paradoxically, plasma concentrations decrease after delivery even in women who are breast feeding. During early lactation, there are pulsatile bursts of prolactin secretion in response to suckling. Ref: Cunningham F.G., Leveno K.J., Bloom S.L., Hauth J.C., Rouse D.J., Spong C.Y. (2010). Chapter 5. Maternal Physiology. In F.G. Cunningham, K.J. Leveno, S.L. Bloom, J.C. Hauth, D.J. Rouse, C.Y. Spong (Eds), Williams Obstetrics, 23e.

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