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Medicine General bddb842d

Which among the following tumor is associated with Polycythemia vera?

A
Osteosarcoma
B
Ovarian tumor
C
Cerebellar haemangioblastoma
D
Pitutary adenoma
High-Yield Explanation
Tumors associated with polycythemia vera are Hypernephroma, Hepatoma, Cerebellar hemangioblastoma, Uterine myoma, Adrenal tumors, Meningioma, Pheochromocytoma. The JAK2 gene located on the sho arm of chromosome 9 and loss of heterozygosity on chromosome 9p due to mitotic recombination is the most common cytogenetic abnormality in Polycythemia Vera. Ref: Harrison's Internal Medicine, 18th Edition, Pages 898-900

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