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Pathology Breast bd1b675d

50 yr old female presented with lump in right breast. She was diagnosed having Luminal A carcinoma. All are true about this cancer except ?

A
M/C subtype
B
Best prognosis
C
ER/ PR negative
D
Response poor to paclitaxel
High-Yield Explanation
Luminal A breast cancer Seen in elderly females M/c subtype ER/ PR positive Her 2 /Neu negative Low proliferation rate Ki 67 : low Best prognosis among subtypes Responsive to hormonal chemotherapeutic agents like tamoxifen and aromatase inhibitors, Respond poorly to non- hormonal chemotherapy drugs like paclitaxel. Immunohistochemistry staining of a tissue biopsy specimen of luminal type A breast cancer:

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