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Surgery GIT bcfb359d

All of the following are true about diffuse gastric cancer according to Lauren's classification except:

A
Familial
B
more common in males
C
undifferentiated
D
more common in the proximal pa
High-Yield Explanation
Lauren Classification System for carcinoma Intestinal Diffuse - Environmental - Gastric atrophy, intestinal metaplasia - Men > Women - Increasing incidence with age - Gland formation - Hematogenous spread - Microsatellite instability - APC gene mutations - p53, p16 inactivation - Epidemic - Distal pa of the stomach - Familial - Blood group 'A' - Women > Men - Younger age group - Poorly differentiated signet ring cells - Transmural/ Lymphatic spread - Decreased E-cadherin - p53, p16 inactivation - Endemic - Proximal pa of the stomach

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