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Pharmacology Anti-Neoplastic Agents bcdb324f

Which of the following anticancer drug causes hemolyticuremic syndrome:

A
Vincristine
B
Vinblastine
C
Cisplatin
D
Mitomycin
High-Yield Explanation
Ans. (d) MitomycinRef.: KDT 6th ed. / 827* After 8-10 months of start of mitomycin-C treatment, the drug leads to endothelial damage* The Renal lesions seen are similar to those seen in idiopathic HUS and include arteriolar fibrin thrombi, expanded sub-endothelial zones in glomerular capillary walls.

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