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Surgery General bc8bcd2b

A new born presented with bloated abdomen sholy after bih with passing of less meconium. A full thickness biopsy of the rectum was carried out. Which one of the following rectal biopsy findings is most likely to be present -

A
fibrosis of submucosa
B
Hyalinisation of the muscular coat
C
Thickened muscularis propria
D
Lack of ganglion cells
High-Yield Explanation
Ans. is 'd' i.e. lack of ganglion cells The diagnosis of Hirschprung's disease is suspected in this neonate, which is confirmed on rectal biopsy by the finding of - lack of ganglion cells.

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