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Pathology Neoplasia bc1e9eeb

Which neoplasm causes pure red cell aplasia?

A
Thymus
B
Breast
C
Hepatocellular
D
Bronchogenic
High-Yield Explanation
Ans. is 'a' i.e., Thymus* Pure red cell aplasia (PRCA) is an uncommon disorder in which maturation arrest occurs in the formation of erythrocytes. Erythroblasts are virtually absent in bone marrow; however, white blood cell and platelet production are normalCauses of PRCA include:* Idiopathic* Autoimmune disease such as SLE* Lymphoproliferative. Association of pure red cell aplasia with T-cell large granular lymphocyte leukemia is well recognized, especially in China* Thymoma* Viral infections such as HIV, herpes, parvovirus B19 (Fifth disease), or hepatitis* Drugs such as mycophenolic acid or erythropoietin* Congenital (Diamond-Blackfan anemia)

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