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Biochemistry General bbc151ac

During replication of DNA, which one of the following enzymes polymerizes the Okazazki fragments?

A
DNA Polymerase I
B
DNA Polymerase II
C
DNA Polymerase III
D
RNA Polymerase I
High-Yield Explanation
Okazaki fragments are sho segments of DNA synthesized on the lagging strand, during the process of DNA replication. DNA polymerase III is a highly "processive" enzyme that has a 1 g unit which acts as a clamp loader for the lagging strand Okazaki fragments, helping the two b subunits to form a unit and bind to DNA. The polymerization of okazaki strands are done by DNA polymerase III. Ref: Lehninger Principles of Biochemistry, 4th Edition, Page 961; Lippincott's Illustrated Reviews: Biochemistry, 3rd Edition, Chapter 11, Pages 401-3

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