Which of the following antineoplastic drug is used to prevent synechiae formation after endoscopic nasal procedures

Topical Mitomycin - C is used to prevent synechiae formation after endoscopic nasal procedures. It is an antitumor antibiotic which acts by inhibiting Topoisomerase - II. It is used topically to avoid systemic side effects. Mitomycin is used for anal carcinoma, bladder carcinoma and laryngotracheal stenosis.