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Microbiology General bb754172

All of the following are functions of CD4 helper cells, except -

A
Immunogenic memory
B
Produce immunoglobulins
C
Activate macrophages
D
Activate cytotoxic cells
High-Yield Explanation
Based on the secretion of different cytokines CD4 Helper T cells are divided into TH1 and TH2. Based on function CD4 helper T cells are divided into- 1) Effector CD4 helper T-cells - These cells secrete cytokines and other products that perform all major functions. - These include TH1 and TH2 helper cells. - Functions are- A) By TH1 cells Activate macrophages Delayed hypersensitivity Cell-mediated immunity The killing of intracellular microbes. e.g. tuberculosis and leprosy Destruction of target cells by- Activate CD8 T cells to become cytotoxic cells. Activate NK cells B) By TH2 cells i)    Activate B cells to develop into antibody-producing plasma cells → facilitate the synthesis of antibodies. 2) Memory CD4 helper T cells Retain the antigenic affinity of the originally activated T cells and are used to act as later effector cells during a second immune response.

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