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Pharmacology Central Nervous system bb535adc

All of the following drugs cause hyperprolactinemia EXCEPT:

A
Haloperidol
B
Chlorpromazine
C
Chlorpromazine
D
Metoclopramide
High-Yield Explanation
Chlorpromazine lowers seizure threshold and can precipitate fits in untreated epileptics. The piperazine side chain compounds have a lower propensity for this action. Temperature control is knocked off at relatively higher doses rendering the individual poikilothermic-body temperature falls if surroundings are cold. The medullary respiratory and other vital centres are not affected, except at very high doses. It is very difficult to produce coma with these drugs. Ref KD Tripati 8thh ed.

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