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Pharmacology General bb25e333

All of the following statements are true about 6–mercaptopurine EXCEPT:

A
It is metabolized by xanthine oxidase
B
It does not cause hyperuricemia
C
Its dose should be reduced when allopurinol is given concurrently
D
It is an active metabolite of azathioprine
High-Yield Explanation
All anticancer drugs can result in hyperuricemia by causing the destruction of excess cells. Azathioprine is an immunosuppressant drug that acts by generating 6-MP. 6-MP is metabolized by xanthine oxidase. Its dose should be reduced when allopurinol is given concurrently.

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