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Pathology General bafb6712

Common variable hypogammaglobulinemia shows ?

A
Decreased B cell count
B
Increased B cell count
C
Compliment opsinization
D
Neutropenia
High-Yield Explanation
Ans. is 'c' i.e., Normal B cells o Most patients with common variable immunodeficiency have normal or near-normal numbers of B cells in the blood and lymphoid tissues. o These B cells, however, are not able to differentiate into plasma cells. o The clinical manifestations are caused by antibody deficiency. o The feature common to all patients is hypogammaglobulinemia, generally affecting all the antibody classes but sometimes only IgG.

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