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Physiology Respiratory System baed89e4

Shift of the oxygen dissociation curve to the right occurs in:

A
Acidosis
B
| 2,3 DPG
C
| Temperature
D
| Pco2
High-Yield Explanation
Ans: a (Acidosis) Ref:Ganong 22nd ed, p. 667Acidosis shifts the ODC to the right. Oxygen dissociation curve demonstrates the percentage of haemoglobin bound with oxygen (saturation) as the oxygen concentration increases. ODC is usually sigmoid shaped.It represents the affinity of hemoglobin for oxygen.Shift to rightShift to left* | CO2 concentration* | CO2 concentration* acidosis* alkalosis* |pH* | pH* | temperature* | temperature* exercise* | Oxygen* hypoxia* | 2. 3 DPG* anaemia * | 2,3 DPG Myoglobin oxygen dissociation curveMyoglobin oxygen dissociation curve is a rectangular hyperbola rather than a sigmoid curve. Since it is to the left of haemoglobin dissociation curve, it takes oxygen from Hb in the blood.

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