A 3-year-old child came to OPD with bruising and generalized petechiae. No hepatosplenomegaly or lymphadenopathyis noted. He have ahistory of viral illness 2 weeks back. On investigation a normal hemoglobin, hematocrit, and white blood cell (WBC) count and differential. The platelet count is 19,000/iL. All of the following are associated with above illness except?
High-Yield Explanation
The diagnosis is ITP. It is the most common form of thrombocytopenic purpura in children. Associated with Ebstein-Barr virus, HIV, Helicobacter pylori Clinical features:- Generalized petechiae and purpura, bleeding from the gums and mucous membranes, Splenomegaly, lymphadenopathy, bone pain, and pallor. Lab findings Platelets count <20,000/mm3 Coagulation normal Platelet size normal/increased Bone marrow- Increased Megakaryocytsis Treatment:- Platelet transfusion IV Ig IV anti D therapy Splenectomy Rituximab