Destruction of zona glomerulosa will deplete

The zona glomerulosa makes up 15% of the mass of the adrenal gland; the zona fasciculata, 50%; .and the zona reticularis, 7%. All three coical zones secrete coicosterone, but the active enzymatic mechanism for aldosterone biosynthesis is limited to the zona glomerulosa, whereas the enzymatic mechanisms for forming coisol and sex hormones are found in the two inner zones. Fuhermore, subspecialization occurs within the inner two zones, the zona fasciculata, secreting mostly glucocoicoids and the zona reticularis, secreting mainly sex hormones. Ref: Ganong&;s review of medical physiology,23rd edition, page: 338