Which of the following does not predispose to leukemia
High-Yield Explanation
Leukemia risk factors
1) General
Gender: Men are more likely to develop CML, CLL and AML than women.
Age: The risk of most leukemias, with the exception of ALL, typically increases with age.
2) Genetics
Family history: First-degree relatives of CLL patients, or having an identical twin who has or had AML or ALL, increases the risk for developing the disease.
Genetic diseases: AML has been associated with Down syndrome, Klinefelter syndrome, Patau syndrome, Fanconi anemia, Bloom syndrome, Ataxia telangiectasia, and Kostmann syndrome, may play a role in the development of leukemia.
3) Smoking
Smoking cigarettes does increase the risk of developing AML
4) Exposures
Radiation : Exposure to high-energy radiation (e.g., atomic bomb explosions) and intense exposure to low- energy radiation from electromagnetic fields (e.g., power lines).
Chemical exposure: Long-term exposure to chemicals like benzene & ethylene oxide is considered to be a risk for leukemia.
Drugs - alkylating agents & topoisomerase II inhibitors increase the risk of AML.
5) Previous Cancer Treatment
Certain types of chemotherapy and radiation therapy for other cancers are considered leukemia risk factors.