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Pediatrics General ba66211a

Primary metabolic bone disorder in scurvy is ?

A
Decreased mineralization
B
Decreased osteoid matrix formation
C
Increased bone resorption
D
Decreased bone mass with normal mineralization and osteoid formation
High-Yield Explanation
Ans. is 'b' i.e., Decreased osteoid matrixo Collagen is a component of osteoid (protein matrix).o Collagen synthesis is deficient in scurvy; therefore, osteoid formation is defective.o On the other hand, in rickets osteoid formation is normal, but mineralization (Calcification) of osteoid is defective.

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