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Medicine General b9f6de48

Hypercoagulation in Nephrotic syndrome is caused by:

A
Loss of Antithrombin III
B
Decreased Fibrinogen
C
Decreased Metabolism of Vitamin K
D
Increase in protein C
High-Yield Explanation
Answer is A (Loss of Antithrombin III) Loss of Antithrombin III contributes to the hypercoagulable state in Nephrotic syndrome `A hypercoagulable state frequently accompanies severe nephrotic syndrome due to urinary losses of antithrmbin reduced serum levels of protein C and S, hyperfibrinogenemia and enhanced platelet aggregation'

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