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General Medicine General b9f427e7

Cytogenetic studies in a 40-year-old woman with follicular lymphoma demonstrate a t14;18 chromosomal translocation involving the bcl-2 gene. Constitutive expression of the protein encoded by the bcl-2 gene inhibits which of the following processes in this patient's transformed lymphocytes?

A
Apoptosis
B
DNA excision repair
C
G1-to-S cell cycle progression
D
Oxidative phosphorylation

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