Which of the following type of aneurysm is associated with adult polycystic kidney disease?
High-Yield Explanation
Patients with ADPKD have a 2-4 fold increased risk subarachnoid or cerebral hemorrhage from ruptured berry aneurysm in the circle of Willis. Saccular aneurysms of the anterior cerebral circulation may be detected in up to 10% of asymptomatic patients on magnetic resonance angiography (MRA) screening. Patients at risk for hemorrhage are: Age more than 50 Family history of intracranial hemorrhage Aneurysms more than 10mm Uncontrolled hypeension Other extrarenal manifestations of ADPKD are: Mitral valve prolapse and aoic regurgitation Hepatic cysts Colonic diveicula Abdominal wall and inguinal hernias Ref: Harrison's Principles of Internal Medicine 18e chapter 284.