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Why is a combination of Ranitidine and Sucralfate better avoided in patient with peptic ulcer disease?

A

Ranitidine combines with sucralfate and prevents its action

B

Sucralfate inhibits ranitidine absorption

C

Ranitidine increases the gastric pH so sucralfate is not able to act

D

Combination of these two drugs produces serious side effects like agranulacytosis

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