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Psychiatry Alcohol-Related Disorders b951a3bb

Earliest symptom showing improvement from classical triad of Wernicke's incephalopathy, to thiamine therapy -

A
Ataxia
B
Ophthalmoplegia
C
Confusion
D
All are equally responsive
High-Yield Explanation
Ans. is 'b' i.e., Ophthalmoplegia Response to thiamine treatment in Wernicke's encephalopathyOcular symptoms :- Earliest to respond, ophthalmoplegia (ocular palsies) improves within hours of thiamine administration. However, horizontal nystagmus may persist.Ataxia :- Ataxia responds more slowly than ocular palsies and half the patients recover incompletely with a residual ataxia.Encephalopathy :- Confusion and other CNS symptoms improve more slowly. As the symptoms of encephalopathy improve, Korsakoff's syndrome may become apparent in some patients.

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