Which among the following is true regarding Menetrier disease?
High-Yield Explanation
Menetrier disease also known as hyperplastic hypersecretory gastropathy, is a disorder in which the gastric mucosal folds are enlarged. This leads to protein loss, parietal cell atrophy, and an increase in mucous cells. It results from profound hyperplasia of the surface mucous cells with accompanying glandular atrophy. It affects males three times more than females, most often after they have a viral illness caused by cytomegalovirus (CMV) or a bacterial infection caused by Helicobacter pylori. Menetrier disease increases a person's risk of stomach cancer. Gastrectomy is needed as treatment.