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Biochemistry Proteins and Amino Acids b91295f2

Number of amino acids in A chain and B chain of insulin is:

A
30, 21
B
28, 32
C
32, 28
D
21, 30
High-Yield Explanation
Ans: d (21 and 30) Ref: Vasudevan,4th ed, p. 108Insulin is a protein hormone with 2 polypeptide chains; the A chain with 21 amino acids and B chain with 30 amino acids.Insulin:T 1/2 of insulin is 5 minutes.Normal daily insulin secretion is 50 units.Tissues independant of insulin - RBC, brain, renal medullary cells, placenta.Amino acids stimulating insulin secretion - leucine and arginine.Pork insulin differs from human insulin by only one amino acid residue.

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