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Pathology General b8a4f86d

All of the following are decreased in nephrotic syndrome, except-

A
Serum transferrin
B
Serum fibrinogen
C
Serum ceruloplasmin
D
Serum albumin
High-Yield Explanation
Ans. is 'b' i.e., Serum Fibrinogen Fibrinogen level is increased in nephrotic syndrome d/t increased hepatic synthesis of fibrinogen. o The largest propoion of protein lost in urine is albumin. o Sometimes, globulins can also be excreted -4 Immunoglobulin excretion increases the susceptibility of infection. o Other proteins which are decreased - Transferrin ---> Microcytic hypochromic anemia. Cholecalciferol binding protein --> hypocalcemia Thyroxine binding globulin --> decreased thyroxine level. Antithrombin III --> hypercoagulability Ceruloplasmin

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