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Biochemistry General b89ec983

A 5 year old female patient complains of deformed shape of legs. Patient is a strict vegetarian. Lab investigations reveal elevated levels of alkaline phosphatase. This patient is suffering from deficiency of a vitamin whose recommended dietary allowance is-

A
300IU
B
400IU
C
500IU
D
600IU
High-Yield Explanation
Deficiency of vitamin D causes rickets in children and osteomalacia in adults. The weight bearing bones are bent to form bow-legs.  In rickets, the plasma level of calcitriol  is  decreased  and  alkaline phosphatase  activity  is  elevated. The daily requirement of vitamin D is 400IU or 10 mg of cholecalciferol. Satyanarayana- Biochemistry, 3rd edition, pg-127

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