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Pathology Lung Tumors b866a965

Mesothelioma associated with which variety of asbestos -

A
Serpentine
B
Amphibole
C
Both the above
D
None of the above
High-Yield Explanation
Ans. is 'b' i.e., Amphibole Asbestos-Related Diseaseso Asbestos is a family of proin flammatory crystalline hydrated silicates that are associated with pulmonary fibrosis, carcinoma, mesothelioma, and other cancers.There are two distinct geometric forms of asbestosi) Serpentine (chrysolite) - most of the asbestos used in industryii) Amphibole (crocidolite)o Both serpentine and amphibole can cause all asbestos related diseases except for mesothelioma, which is usually associated with amphibole (crocidolite).Asbestos related diseases consist of:o Localized fibrous plaques which may be calcifiedo Diffuse pleural fibrosiso Pleural effusiono Parenchymal interstitial fibrosis (asbestosis)o Lung carcinoma Most common neoplasm associated with asbestos exposureo Mesothelioma of pleura and peritoneum - most specific neoplasm associated with asbestos exposureo Laryngeal and colon carcinomaso Stomach carcinomaNote: - Concomitant cigarette smoking greatly increase the risk of lung carcinoma but not that of mesotheloma.

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