Which of the following production is noted in Cushing's Syndrome
High-Yield Explanation
Cushing syndrome
Cushing syndrome is characterized by an excess production of cortisol.
The most common cause of Cushing syndrome is exogenous hypercortisolism, i.e., administration of exogenous glucocorticoids.
The cause of endogenous hypercortisolism (endogenous Cushing syndrome) are : -
i) ACTH producing pituitary microadenoma →
It is the most common cause of endogenous hypercortisolism and this form of Cushing syndrome is referred to as Cushing disease.
ii) Hypersecretion of cortisol by an adrenal adenoma, carcinoma or nodular hyperplasia.
iii) The secretion of ectopic ACTH by a nonendocrine neoplasm, e.g., small cell carcinoma of the lung.