Mechanism of analgesia is bya) Nociceptin stimulationb) Nocistatin stimulationc) Anandamide receptorsd) Nicotinic & cholinergic receptors

Nocistatin stimuli inhibit nociceptors and produce analgesia. Anandamide (a cannabinoid) produces analgesic effect by binding to CB1 receptors. Acetylcholine and nicotinic cholinergic receptors (subunits α4 and β 2) are involved in regulation of pain.