Poor prognostic indicator in ALL-

Poor prognostic factors in ALL Age less than two years, largely because of the strong association of infantile ALL with translocation involving MLL gene. Presentation in adolescence oor adulthood Peripheral blood blast count greater than 100000 which probably denotes a high tumour burden. Reference : Robbins and Cotran Pathologic basis of disease.South Asia Edition volume 1.page no. 592