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Gynaecology & Obstetrics Contraceptives b7c9f3b1

Centchroman is :

A
New drug for fibroids
B
New drug for endometriosis
C
Injectable contraception
D
Nonsteroidal oral contraception
High-Yield Explanation
Centchroman/ Ormeloxifene Nonsteroidal estrogen antagonist : SERM (Selective estrogen receptor modulator) Developed at CDRI, Lucknow. Tablets of 30 mg to be taken twice a week for 3 months and then once a week for contraception . Has a weak Estrogenic and potent antiestrogenic effect--acting mostly on the endometrial target organs to suppress proliferation of the endometrium, thereby interfering with nidation of the embryo; Causes asynchrony between the Ovulation and the endometrial development Other uses: Breast cancer, benign breast diseases, abnormal uterine bleeding

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