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Pathology Female Genital Tract b76b5d23

Endometriotic lesion histology represents it's?

A
High estrogen
B
High progesterone
C
High cholesterol
D
High levels of prolactin
High-Yield Explanation
Ans. (a) High estrogen(Ref: R 9th/p 721)Increased estrogen production by endometriotic stromal cells, due in large part to high levels of the key steroidogenic enzyme aromatase, which is absent in normal endometrial stroma. Mutations in specific genes (PTEN and ARID1A) in endometriotic cysts.

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