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Pharmacology Anaesthesia b7683d07

All are true about Bupivacain EXCEPT

A
Less cardiotoxic than lignocaine
B
Dose increases with adrenaline
C
Long acting
D
Cannot given in veins
High-Yield Explanation
(Less cardiotoxic than lignocaine) (391 Less' 13th) (357-KDT 6th)* 0.25% bupivacain or 0.5% lidocaine both with adranaline are suitable. The dose of bupivacain should not exceed 2mg / kg (456 - Lees)* Bupivacaine causes more sensory than motor block* It is not recommanded for intravenous regional analgesia because leakage post the tourniquet in to blood stream may cause toxic or even fatal complication* The duration of effect is between 5 and 16 hours - it is one of the longest - acting local analgesics known* Lignocaine - It is less toxic than bupivacain but cardiotoxic and CNS symptoms of poisoning may occur* The new local anaesthetics levobupicaine and ropivacaine undoubtedly safer than bupivacaine, But case reports of convulsions and cardiac arrest are emerging (385 - Lees 13th)

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