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Medicine Haematology b6d2ff6c

The following set of finding is seen in DIVC

A
Increased fibrinogen, increased antithrombin III increased thrombin-antithrombin III comolexes
B
Increased FDP, decreased PT, increased antithrombin III
C
hicreased FDP, prolonged PT, increased thrombin- antithrombin complexes
D
Increased FDP, prolonged PT, reduced platlets
High-Yield Explanation
In disseminated intravascular coagulation (DIC), coagulation is usually activated when blood is exposed to tissue factor. Severe, rapid-onset DIC causes severe thrombocytopenia, prolonged PT and PTT, a rapidly declining plasma fibrinogen level, and a high plasma d-dimer level Fibrinogen degradation product (FDP) testing is commonly used to aid in the diagnosis of disseminated intravascular coagulation (DIC). Increases in serum FDP levels can be caused by the following : DIC. Post fibrinolytic therapy. Ref Davidson 23rd edition pg 876

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