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Biochemistry AIIMS 2017 b69b1f70

Which amino acid does not include post translational modification?

A
Selenocystiene
B
Triiodothyronine
C
Hydroxy-proline
D
Hydroxy-lysine
High-Yield Explanation
Selenocysteine (21st amino acid) & Pyrrolysine (22nd amino acid) Formed by co-translational modification Not by post-translational modifications. Selenocysteine and Pyrrolysine 21st amino acid-Selenocysteine- UGA 22nd amino acid - Pyrrolysine - UAG Both UGA, UAG are stop codon but co-translational modification can give rise to amino acid selenocysteine and pyrrolysine. co-translational modification. Enzymes that use selenocysteine as their active sites are called Seleno Proteins. Selenocysteine containing proteins: Glutathione peroxidase Thioredoxin reductase selenoprotein P 5' deiodinases

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