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HEPARIN - side effects- BOAT-code Bleeding osteoporosis Alopecia Thrombocytopenia Contraindications 1. Bleeding disorders, heparin-induced thrombocytopenia. 2. Severe hypeension, (risk of cerebral hemorrhage), threatened aboion, piles, g.i. ulcers (risk of aggravated bleeding). 3. Subacute bacterial endocarditis (risk of embolism), large malignancies (risk of bleeding in the central necrosed area of the tumor), tuberculosis (risk of hemoptysis).4. Ocular and neurosurgery, lumbar puncture. 5. Chronic alcoholics, cirrhosis, renal failure. 6. Aspirin and other antiplatelet drugs should be used very cautiously during heparin therapy. ESSENTIALS of MEDICAL PHARMACOLOGY SIXTH EDITION K. D TRIPATHI Page:597,598