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Pharmacology General b5c330b2

Fluoroquinolones act on -

A
DNA histone proteins
B
DNA gyrase
C
Camp
D
mRNA polymerise
High-Yield Explanation
Ans. is 'b' i.e., DNA gyrase o Fluoroquinolones (including ciprofloxacin) inhibit DNA gyrase and topoisomerase IV. For gram negative bacteria, the primary target is DNA gyrase, while topoisomerase IV is inhibited in gram positive bacteria.

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